5-Day Tour from Rome: Florence, Venice, Siena and Tuscany

5-Day Tour from Rome: Florence, Venice, Siena and Tuscany

English, French
5 Days, 4 Nights
Free! cancellation up to 7 days


  • UNESCO sites Assisi, Siena, Florence, Venice
  • Transport by deluxe motorcoach (free Wi-Fi connection on board)
  • Assistant for the entire tour duration
  • Florence's Uffizi Gallery with skip-the-line tickets
  • Venice's St. Mark's Basilica with skip-the-line


Visit the highlights of Italy on a 5-day escorted tour from Rome visiting Assisi, Siena, Florence, Bologna, Padua, Venice and Tuscany's Wine Region.

Day 1: Rome, Assisi, Siena, Florence (dinner included)

Departing at 7:15 AM from Hotel Diana by a deluxe coach, you will arrive in Assisi, ready to explore, at your own leisure, this tiny town surrounded by walls, built in the Middle Ages. Take your time to visit the Basilica of St. Francis, where you will see masterpieces by Giotto and Cimabue and, then, have free time for lunch (not included). Board on the bus to reach Siena, a Unesco World Heritage Site, known for the Palio, the historical horse race around the shell-shaped town square: Piazza del Campo. Next, you will continue on to Florence, where you will check in at your hotel (Hotel Mediterraneo 4*, Tourist or 1st Category) before enjoying dinner and a well-earned night of rest.

Day 2: Florence (breakfast and lunch included)

After breakfast, you will spend the day venturing around beautiful Florence, the so-called “Cradle of Renaissance", where, thanks to Michelangelo, Italian art reached the sublime.

Based on Etruscan-Roman origins, the city flourished in the Middle Ages as a free “Comune” and was further refined during the Renaissance. You will be fascinated by the uncountable monuments, churches and buildings as Santa Maria del Fiore, more commonly referred to as the Duomo. On your visit, you will be amazed by its magnificent dome built by Filippo Brunelleschi. Cross a small piazza to see the “Campanile” (partly designed by Giotto) and the Baptistery, with its bronze doors where Michelangelo imagined the “Gates of Paradise.” In the heart of the city, you will see Piazza della Signoria, Palazzo della Signoria (also known as Palazzo Vecchio) and the Basilica of Santa Croce. Lunch in a typical Tuscan restaurant in Piazza Santa Croce and then spend the afternoon strolling the cobblestone streets of Florence on your own or take a short trip to Pisa (optional), one of the four main historical Marine Republics of Italy. There, you will tour the Piazza dei Miracoli with the Duomo, the Leaning Tower and the Baptistery. Dinner at leisure, overnight stay in Florence (Hotel Mediterraneo 4*, Tourist or 1st Category).

Day 3: Florence, Bologna, Padua, Venice (breakfast and lunch included)

After breakfast in Florence, departure to Bologna. There, you will discover the elegant city center with its “porticos”, it’s shopping streets and so on. From Piazza Malpighi you will walk to Piazza del Nettuno and Piazza Maggiore in the heart of the city, King Renzo’s Palace, Palazzo Podestà and the Basilica of San Petronio, one of the biggest in the world. Bologna is a real gourmet heaven… Don’t miss out on a tasty meal at your own leisure! In the afternoon, continue toward Padova, with Basilica of Sant’Antonio: one of the most visited churches by pilgrims of the catholic world. Later in the afternoon, arrival in Venice: the City of Love, one of the most romantic cities of the whole world and, undoubtedly the most beautiful city built by man! Check in at your hotel for dinner and overnight stay (Tourist Category: Hotel Delfino 4* in Mestre; 1st Category: Hotel Carlton on the Gran Canal 4* on Venice Island).

Day 4: Venice (breakfast and dinner included)

After breakfast, enjoy your private water-taxi transfer to Piazza San Marco, with skip the line tickets to visit the splendid St. Mark’s Basilica and, after this, check out the most iconic places of the “Floating City”: the Palazzo dei Dogi, symbol of Venice’s glorious past, the legendary “Bridge of Sighs”. Spend the afternoon roaming along Venice’s canals at your leisure and then return to the hotel for dinner and overnight (Tourist Category: Hotel Delfino 4* in Mestre; 1st Category: Hotel Carlton on the Gran Canal 4* on Venice Island).

Day 5: Venice, Montepulciano (Tuscany's Wine Region), Rome (breakfast included)

After breakfast, departure from Piazzale Roma heading to Tuscany, world-known for its landscapes, its churches and castles and its delicious wines. You will proceed to Val di Chiana with a stop in Montepulciano, a medieval town rich in history and art. Known for its wine called "nobile", on purchase in local wine houses, Montepulciano also hosts an annual jazz and wine festival every July. Spend the afternoon discovering Montepulciano at your own pace, enjoying free wine tastings in many wine shops and free time for shopping. In the evening, you will arrive in Rome, where the tour ends.


  • Local guides
  • Headset (You will hear only your language through the headset. )
  • Skip-the line entrance tickets
  • 4 overnights in hotel (standard room) on a BB basis
  • 4 breakfasts, 2 lunch, 2 dinners

Not included

  • Food and beverages not mentioned in "Included"
  • Transport from/to airport
  • Pickup at the hotel on the first day

Price & Payment

5-Day Tour from Rome: Florence, Venice, Siena and Tuscany

Per Person (2 Per Room)
873 $
Per Person (1 Per Room)
1153.50 $
Per Person (3 Per Room)
873 $
Per Child (1 Per Room with parents)

More information

Note that

  • One piece of luggage per person is allowed
  • You can choose to take this tour with accommodation in Hotel Delfino in Mestre (4*, Tourist Category) or Hotel Carlton in Venice (4*, 1st Category)

COVID-19 Measures

  • Enjoy the activity safely! We adopt the recommended legal and sanitary measures to prevent the spread of COVID-19. Among them, keeping the safety distance, the use of masks for both the guide and the participants, small groups, disposable headphones, vehicle disinfection before and after each service, disinfectant gel available, avoiding the use of printed material, among others, according to the specific type of activity.

Additional details

  • The tour is not wheelchairs-friendly.
  • Please note that some of the places we are going to visit have a dress code: no sleeveless blouses, no miniskirts, no shorts, no hats.


Cancellation up to 7 days before the date of the activity: no charge & 100% refund / Less than 7 days, late arrival or no show: no refund will be provided.

Starting point

Hotel Diana Via Principe Amedeo, 4, Rome. All the details of the meeting point will be indicated in the voucher you will receive at the end of your reservation.
5-Day Tour from Rome: Florence, Venice, Siena and Tuscany
from 873 $

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Nattivus guarantees you the best price available at the time of making your reservation. However, if you find a lower price offer in the same currency as the original purchase, for the same dates, conditions and characteristics of the booked activity, we will match the price, refunding you the difference. This reservation must be a minimum of € 20.

For this, it will be necessary to present a complete and final budget as proof, which includes all the concepts of the reservation: date, duration, currency, price, participants, modality, management expenses, etc., issued by another agency legally authorized to operate in Spain, the same day that you have made your reservation with Nattivus, from which any additional discount will be excluded for belonging to a specific group.

To request a refund, send a message to info@nattivus.com with your name and booking number along with a proof of the lower price. Refunds of the price difference will be processed in the same payment method used for the original reservation.


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Single payment: The payment of the total amount will be made at the time of booking. Cash payments are not accepted on the day of the visit.

Payment the day of the tour: A first payment of a percentage of the total will be required at the time of booking and the second payment of the remaining amount you will pay at the destination on the day of the activity, in cash or card, as indicated. Please note that only payments in local currency will be accepted (for example in Spain only EUROS will be accepted).

Payment in 2 installments: It will be necessary to pay a first payment of a percentage of the total amount when making the reservation. The second payment of the remaining amount must be made before the day of the activity, on the deadline indicated. In case of reaching this date and the pending amount has not been paid, the reservation will be cancelled and the amount paid initially will be refunded. Please note that this payment method is applied to reservations whose departure date is more than 30 days from the reservation date. For reservations whose departure date is within the following 30 days, 100% of the amount will be charged at the time of booking.


Cancellation up to 7 days before the date of the activity: no charge & 100% refund / Less than 7 days, late arrival or no show: no refund will be provided. If you need to cancel your booking, please, email us at info@nattivus.com.

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